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About Mission and Outline Background Activities For Community Message from Executive Director Toward the Development of Personalized Healthcare through the Promotion of Industry-Academia Collaboration Organization and Members Department of Community Medical Supports Department of Preventive Medicine and Epidemiology Department of Biobank Department of Integrative Genomics Department of Health Record Informatics Department of Education and Training Department of Public Relations and Planning General Affairs and Planning Sector Cohort Studies Sector Integrated Biobank Sector Integrated Omics Sector Group of Planning Group of Public Relations Group of Education and Training Group of Return of Genomic Results Center for Promotion of Cohort Studies Center for Health Survey Promotion Group of Brain Imaging and Research Group of Biobank Center for Biobank Utilization and Academia-Industry Partnership Group of Integrated Database Systems Group of Information Management for Genome-Cohort Study Group of Privacy Controls Group of Sequencing Group of Microarray-based Genotyping Group of Metabolomics Group of Metagenomics and Microbiome Group of Omics Data Analysis Center for Genome-Wide Association Study Office of Nihonbashi Branch Operation Center for Genome Platform Projects Policy Site Policy Social Media Policy Research Cohort Study and Biobank Community-Based Cohort Study (TMM CommCohort Study) Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study) Integrative Genomics Publications Facilities and Equipment Researchers Specimen and Data Collection Ethical Issues ToMMo's Library News Timeline sitemap links access & contact JAPANESE Large Small A A Top ResearchThe analysis of the whole genome sequence of 69,000 individuals has been completed, and 54KJPN is now available News Timeline all News Events Research Monthly archives 2024, April 2024, February 2024, January 2023, November 2023, October 2023, September 2023, August 2023, July 2023, June 2023, May 2023, April 2023, March 2023, January 2022, December 2022, November 2022, October 2022, September 2022, July 2022, May 2022, April 2022, January 2021, December 2021, November 2021, September 2021, August 2021, July 2021, June 2021, March 2021, January 2020, November 2020, October 2020, September 2020, August 2020, July 2020, June 2020, April 2020, March 2020, February 2020, January 2019, December 2019, November 2019, September 2019, August 2019, July 2019, May 2019, April 2019, March 2019, February 2019, January 2018, December 2018, November 2018, October 2018, September 2018, August 2018, July 2018, June 2018, May 2018, March 2018, February 2018, January 2017, December 2017, November 2017, October 2017, September 2017, August 2017, July 2017, June 2017, May 2017, March 2017, February 2017, January 2016, December 2016, November 2016, October 2016, September 2016, August 2016, July 2016, June 2016, May 2016, April 2016, March 2016, February 2016, January 2015, December 2015, November 2015, October 2015, September 2015, August 2015, July 2015, June 2015, May 2015, April 2015, March 2015, February 2015, January 2014, November 2014, October 2014, August 2014, July 2014, April 2014, March 2014, February 2014, January 2013, November 2013, August 2013, July 2013, June 2013, May 2013, April 2013, February 2013, January 2012, December 2012, November 2012, October 2012, September 2012, April 2012, March 2012, February The analysis of the whole genome sequence of 69,000 individuals has been completed, and 54KJPN is now available Research: 2023/07/28 ToMMo has completed a total of 69,000 individuals the whole genome sequence analysis of the general Japanese population. These are from our cohort studies of more than 150,000 participants and are one of the world's largest-scale whole genome analyses of a general population. Based on the analysis data of 54,000 of these 69,000 individuals, the Japanese whole-genome reference panel 54KJPN is now released on June 26, 2023, on the jMorp (Japanese Multi Omics Reference Panel). Details on the data available Whole Genome Information of 69,000 people ToMMo has been analyzing DNA provided by the individuals who are participants in the cohort studies conducted as part of the Tohoku Medical Megabank Project. The data of approximately 20,000 individuals has undergone whole genome sequence analysis since its previous release (38KJPN) in June 2022. The analyzed data will then be provided sequentially to researchers nationwide. The quality information of each analyzed data is available on the web page of Sample Repository. Japanese Whole Genome Reference Panel 54KJPN The Japanese whole-genome reference panel 54KJPN was constructed by selecting 54,000 individuals, who are assumed to be unrelated to each other to avoid frequency bias, from the whole genome sequence of 69,000 individuals. The table below compares the number of genome variations in the past and in new versions. Comparing 54KJPN to 38KJPN, the previous version, as announced in June 2022, the number of individuals increased by 16,000 and the number of SNVs and INDELs discovered increased by approximately 10 million and 2.3 million, respectively.   Number of SNVs Number of INDELs 14KJPN 106,705,823  13,130,321  38KJPN 176,329,248  21,824,946  54KJPN 187,086,901  24,193,448  Additionally, the HLA panel 38KJN-HLA has expanded into the 54KJPN-HLA. Related Link Completion of 50,000 Japanese whole genome sequence analysis and release of whole genome reference panel of 38,000 Japanese individuals (38KJPN) （2022/07/19） Genome information for 14,000 people is now available -jMorp 2021 major update-（2021/12/27） Allele frequency data of the 8.3KJPN has been released from dbSNP（2021/06/29） Release of locations and allele frequencies of all SNVs in whole genome sequences of 2,049 Japanese individuals （2016/06/21） Constructing the First Version of the Japanese Reference Genome [Press Release]（2021/01/29） News Timeline Tweet About Mission and Outline Background Activities For Community Message from Executive Director Organization and Members Policy Research Cohort Study and Biobank Integrative Genomics Publications Facilities and Equipment Researchers Ethical Issues Specimen &＃038; Data Collection ToMMo's Library News Timeline access & contact sitemap links JAPANESE Large Small A A Copyright(C) Tohoku University Tohoku Medical Megabank Organization All Rights Reserved. sitemap access & contact About Research Ethical Issues Specimen &＃038; Data Collection ToMMo's Library News Timeline access & contact sitemap links Japanese